Periowave Photodisinfection- The Unique 3 Prong Attack on Periodontal (Gum) Disease

The most common of human infections is gum (or periodontal) disease, affecting up to 80% of the population at some point in their lives. The primary issue is that teeth are non-shedding surfaces and so bacteria, in the form of biofilms, can easily establish themselves on the surface of a tooth where tooth-brushing or other mechanical debridement is lacking.

Gum disease is caused by the presence of gram-negative bacterial biofilms growing in the periodontal pockets underneath the gum line. These gram- negative pathogens associated with gum disease are largely anaerobic, thriving in environments with little to no oxygen. Bacteria, and their associated virulence factors, cause an immune response by the body. Gram negative pathogens associated with gum disease are not “good” bugs (commensals), that is, they are not part of the body’s natural flora. One pathogen, Porphyromonas  gingivalis, according to Dr. Richard Darveau, Dean  of the University of Washington’s Dental School, has demonstrated an ability to modify the behaviour of oral commensals, turning bacteria that are normally ‘good’ bacteria into ‘bad’.  Perio-pathogens,  such as Porphyromonas  gingivalis, up-regulate the body’s production of proteolytic enzymes, cytokines and other pro-inflammatory factors in order to sustain their continued growth. The result is inflammation with widespread impact on the local as well as systemic physiology.

Gum disease has been associated with a number of serious systemic conditions including heart disease, stroke, diabetes, pre-diabetes, cancer, Alzheimer’s and pre-term births. The most notable local symptoms of the effects of these perio-pathogens  are red inflamed gums and the loss of alveolar bone supporting the teeth. Gum disease is responsible for about two thirds of tooth loss. Scaling and root planing (SRP), the historic standard of care leaves as much as 60% of the perio-pathogens behind to continue the disease process, which is why the SRP protocol requires a 3 month retreatment recall program. Photodisinfection, however, has been able to double the outcomes of SRP in clinical trials.

Effective gum disease eradication requires 3 components which only Periowave Photodisinfection provides: the instantaneous elimination of virtually all of the gram negative anaerobic perio-pathogens, the destruction of their associated virulence factors, and the inactivation of the host inflammatory factors. When removing both the biofilm and the inflammation simultaneously, the body is then able to repair itself through soft and hard tissue regeneration.  Periowave Photodisinfection has been proven to rapidly and effectively kill the micro-organisms located in periodontal biofilms and to destroy the virulence factors produced by these pathogens. Most importantly, Periowave has a unique advantage, an ability to rapidly and substantially reduce protease activity, providing a high-level suppression of pro-inflammatory cytokines needed to restore oral health.

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